Skip to main content
. 2015 Dec 31;10(12):e0146109. doi: 10.1371/journal.pone.0146109

Table 3. Physical, plasma, and urine parameters.

  Baseline
Parameter Sham IR IR+rIPerC IR+rIPC
BW, g 258 ± 2.9 262 ± 2.9 268 ± 3.1 261 ± 2.2
Intakewater, mL 46 ± 4.8 40 ± 2.6 44 ± 4.2 54 ± 2.8
Intakefood, g 34 ± 8.9 19 ± 1.4 28 ± 8.9 19 ± 0.9
CrCl, mL/min/kg 2.8 ± 0.4 3.1 ± 0.4* 3.2 ± 0.3* 2.4 ± 0.3*
Pcr, μmol/L 48 ± 5.4 56 ± 7.0 48 ± 2.8 56 ± 5.6
Purea, mmol/L 10 ± 0.8 11 ± 1.2* 12 ± 0.7* 12 ± 0.7*
  Day 3
Parameter Sham IR IR+rIPerC IR+rIPC
BW, g 260 ± 5.1 249 ± 4.3 249 ± 3.7 241 ± 2.3*
Intakewater, mL 35 ± 4.0 34 ± 3.3 32 ± 3.4 35 ± 2.5
Intakefood, g 15 ± 0.7 9 ± 1.0* 8 ± 1.3* 7 ± 0.5*
CrCl, mL/min/kg 5.2 ± 0.4 1.7 ± 0.4* 1.7 ± 0.3* 1.2 ± 0.3*
Pcr, μmol/L 34 ± 1.8 156 ± 46.4* 142 ± 33.7* 195 ± 32.3*
Purea, mmol/L 9 ± 0.2 28 ± 6.3* 26 ± 5.3* 34 ± 5.1*
 
  Day 7
Parameter Sham IR IR+rIPerC IR+rIPC
BW, g 251 ± 4.2 241 ± 5.1 245 ± 4.0 234 ± 1.9
Intakewater, mL 27 ± 3.0 41 ± 3.3* 40 ± 3.2 42 ± 3.6*
Intakefood, g 18 ± 0.7 16 ± 1.2 17 ± 1.0 15 ± 0.8
KW, g/100 g BW 5 ± 0.2 11 ± 1.0* 11 ± 1.1* 12 ± 0.7*
CrCl, mL/min/kg 6.0 ± 0.6 3.5 ± 0.4* 3.6 ± 0.3* 2.8 ± 0.2*
Pcr, μmol/L 25 ± 2.0 55 ± 11.3* 43 ± 2.7 61 ± 5.4*
Purea, mmol/L 6 ± 0.4 15 ± 3.6* 12 ± 0.9* 16 ± 1.8*

Values are presented as means ± SEM. Group means were compared using either one-way analysis of variance followed by Bonferroni’s multiple comparison post-test or Kruskal-Wallis test with Dunn's multiple comparisons post-test.

*P < 0.05 vs. sham.

BW, body weight; Intakewater, 24-hour water intake; Intakefood, 24-hour food intake; KW, kidney weight; CrCl, creatinine clearance; Pcr, plasma creatinine; Purea, plasma urea; Uoutput, urinary output; FENa, fractional excretion of sodium; IR, ischemia-reperfusion; rIPerC, remote ischemic perconditioning; rIPC, remote ischemic preconditioning.