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. Author manuscript; available in PMC: 2017 Jan 1.
Published in final edited form as: Mol Cell Neurosci. 2015 Nov 17;70:11–21. doi: 10.1016/j.mcn.2015.11.004

Figure 1. Mutations in Drosophila genes encoding homologs of mammalian PSD proteins lead to a reduction in GluRIIA cluster sizes.

Figure 1

(A) Confocal images of third instar larval 6/7 NMJs immunolabeled with α-HRP to label presynaptic motor neurons (magenta) and α-GluRIIA (green) to label postsynaptic glutamate receptor clusters containing the GluRIIA subunit. Inset panels show high resolution terminal boutons. Scale bar = 20 µm. (B) Histogram showing GluRIIA cluster sizes for genotypes represented in A. (C) Quantification of the number of boutons (left) and branches (right) indicative of presynaptic motor neuron morphology.