Table 2.
Change in body weight (in g) after 14 days of treatment with vehicle, sertraline, E2, ERα or GPR30 agonists
| Vehicle (n=14) |
Sertraline (n=7) |
E2-5µg (n=7) |
DPN-5µg (n=7) |
DPN-10µg (n=6) |
G1–5µg (n=7) |
G1–10µg (n=7) |
|---|---|---|---|---|---|---|
| +36±7.5a | +31±9.2 | −1*±15.0 | +29±6.4 | +41±9.6 | +29±9.0 | +38±4.5 |
All the numbers are change in body weight ± SD after chronic treatment with drugs: the weight of the rat at the end of treatment was subtracted from the weight of the rat at the beginning of the treatment.
One way ANOVA was carried out. There was a significant main effect between groups (F(6,48)=17.04, p < 0.001). Dunnett’s post-hoc analysis was carried out
p < 0.001, comparing all groups with vehicle.