FIG. 2.
(a) The real component of the Clausius–Mossotti factor–Re(fCM) calculated for human red blood cells, plotted for various dilutions of blood plasma vs applied AC excitation frequency. The red blood cells exhibit a strong negative DEP response at σplasma = 1.2 S/m and 1 MHz, repelling them from the cross flow filter entrance. Simulated electric field (b) and applied DEP force (c). These simulations are representative of a segment of the cross flow filter/primary channel interface, as shown in Figs. 1(b) and 1(c′). The dotted line indicates the entrance of the cross flow filter structure. The area within this filter, to the left of the line has a depth of 1.2 μm, while the primary channel to the right of this line has a depth of 25 μm. (b) The distribution of the electric field generated by the electrodes when energised at 8 V, peak to peak. (c) The gradient of electric field square, which is proportional to the applied DEP force.