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. Author manuscript; available in PMC: 2017 Jan 1.
Published in final edited form as: Trends Endocrinol Metab. 2015 Nov 29;27(1):1–10. doi: 10.1016/j.tem.2015.11.002

Figure I. Typical layered dWAT structures in rodents and humans.

Figure I

A) Section of dWAT from a C57/Bl6 mouse maintained at room temperature. The dWAT contains several layers of adipocytes (arrowheads) placed parallel to the panniculus carnosus (PC).

B) Section of dWAT from a C57/Bl6 mouse after cold exposure of 6°C for 4 days; both hypertrophy and hyperplasia can be seen (area indicated with a black line). dWAT can quickly react to different types of physical and pharmacological stimuli with significant modulation of its thickness. Slides A and B courtesy Dr. Min Kim, Touchstone Diabetes Center, UT Southwestern Medical Center, Dallas.

C) Human adipocytes are congregated around the single pilosebaceous units (PU) producing the “dermal cones” (arrowhead). Morphological characteristics of these cones are dependent on the body area and the phase of HF cycle. Slide courtesy Dr. Travis Vandergriff, Department of Dermatology, UT Southwestern Medical Center, Dallas.