Figure 1. The effect of HIV and ΔNefHIV infection on the structure (A) and function (B, C) of plasma high density lipoprotein.
A – Analysis of distribution of HDL among different subfractions in plasma of HIV-negative subjects and patients infected with WT HIV or ΔNefHIV. *p<0.05; **p<0.01 versus HIV negative subjects. B- Cholesterol efflux from human THP-1 monocyte-macrophages to 1% plasma from HIV-negative subjects and patients infected with WT HIV or ΔNefHIV. C- Cholesterol efflux from human THP-1 monocyte-macrophages to 1.1% apoB-depleted plasma from HIV-negative subjects and patients infected with WT HIV or ΔNefHIV. *p<0.05 versus HIV-negative; #p<0.05 versus ΔNefHIV.