Table 2.
Lipid Species | HIV Negative | WT HIV | ΔNef-HIV |
---|---|---|---|
PS 36:1 | 1418.5 ± 935.8 | 259.5 ± 259.9** | 7733.5 ± 9425.3# |
PS 38:3 | 299.8 ± 158.4 | 53.8 ± 91.9* | 1559.4 ± 1791.7# |
PS 40:5 | 123.0 ± 65.5 | 13.6 ± 33.4** | 590.9 ± 659.4# |
PS (total) | 2161.5 ± 1317.7 | 334.2 ± 121.4* | 10,772.2 ± 12,619.5# |
dhCer 20:0 | 20.8 ± 5.6 | 23.4 ± 9.1 | 115.7 ± 125.8* |
Cer 18:0 | 80.4 ± 16 | 102.9 ± 26.6 | 140.7 ± 76.9* |
SM 32:0 | 423.0 ± 84.8 | 512.0 ± 136.4 | 666.2 ± 176.0* |
SM 34:0 | 4,369 ± 686.2 | 5,402.1 ± 1,442.6 | 6,326 ± 803.1** |
PE(O-36:6) | 34.3 ± 10.4 | 71.7 ± 44.9 | 95.4 ± 32.5** |
dhCer (total) | 519.0 ± 77.7 | 571.9 ± 254.3 | 1439.2 ± 1033.8* |
PI 34:0 | 153.5 ± 58.0 | 362.2 ± 298.8* | 342.8 ± 287.7 |
dhCer 16:0 | 46.3 ± 6.7 | 71.5 ± 15.7* | 120.7 ± 70.5** |
dhCer 18:0 | 46.1 ± 11.4 | 79.6 ± 22.0* | 194.1 ± 184.3* |
DHC 20:0 | 111.3 ± 38.4 | 85.0 ± 38.6 | 256.2 ± 249.5# |
PE(22:6/0:0) | 1378.0 ± 402.6 | 1723.5 ± 836.7 | 1042.8 ± 168.4# |
PS 40:6 | 128.4 ± 53.9 | 36.6 ± 49.7 | 572.1 ± 619.6# |
Abbreviations: dhCer, dihydroceramide; Cer, ceramide; DHC, dihexosylceramide; PE, phosphatidylethanolamine; PE(O), alkylphosphatidylethanolamine; PI, phosphatidylinositol; PS, phosphatidylserine; SM, sphingomyelin;
p < 0.05 vs HIV Negative;
p < 0.01 vs HIV Negative;
p < 0.05 vs WT HIV (ANOVA)