Table 3.

Selected predicted targets of miRNAs depended on presence of Nef

microRNA	Predicted targets	Validated targets	Gene name	Reference to HIV
hsa-miR-199b-3p	ABCA1		ATP-binding cassette transporter A1	Many
	ABCA13		ATP binding cassette, transporter A13
	LRP2		LDL receptor-related protein 2
hsa-miR-409-3p	ABCA12		ATP-binding cassette, transporter A12	Many
	ABCB10		ATP-binding cassette, transporter B10
	LRP		LDL receptor-related protein	PMID:22412921
hsa-miR-320a	CANX		Calnexin	PMID: 25170080
	XPO1/CRM1		Exportin-1	PMID: 22318151
hsa-miR-24-3p	ABCB9	ABCB9	ATP-binding cassette transporter B9
hsa-miR-382-5p	LRP12		LDL receptor-related protein 12
hsa-miR-130a-3p	LRP8		LDL receptor-related protein 8
	LDLR	LDLR	LDL Receptor	PMID:24191141
	ACSL4		acyl-CoA synthetase long-chain family member 4
	PLCB1		phospholipase C, beta 1	PMID:23555755
	CD69		CD69	PMID:25340508
hsa-miR-4433b-5p	VLDLR		VLDL Receptor	PMID:25394062
	SMPD3		Neutral sphingomyelinase II
hsa-miR-7-5p	APOA2		Apolipoprotein A2	PMID:21978398
	IRS2	IRS2	Insulin receptor substrate 2	PMID:15590971
	ACSL4	ACSL4	acyl-CoA synthetase long-chain family member 4
	IDE	IDE	insulin-degrading enzyme	PMID:17026490
hsa-miR-218-5p	ACSL1		acyl-CoA synthetase long-chain family member 1
hsa-miR-376c-3p	VLDLR		VLDL receptor	PMID:25394062
	ACSL1		acyl-CoA synthetase long-chain family member 1
	ALCAM		activated leukocyte cell adhesion molecule	PMID25420915
hsa-miR-590-5p	IL12A		Interleukin 12A	PMID: 12444143
hsa-miR-326	SLC2A1/GLUT1		MFS transporter, solute carrier family 2	PMID: 24335483
hsa-miR-193a-5p	SRF		Serum response factor	PMID: 12120892
hsa-miR-146a-5p	CCL8/MCP-2	CCL8/MCP-2	Chemokine (C-C motif) ligand 8	PMID: 20181935
hsa-let-7i-5p	TBP	TBP	TATA Box motif	PMID: 25336585
hsa-miR-122-5p	HMOX1	HMOX1	Heme oxygenase (decycling) 1	PMID: 24752012
	BACH1	BACH1	BTB and CNC homology 1	PMID: 24752012
hsa-miR-134-5p	SHP	SHP	Src homology-2 domain-containing protein tyrosine phosphatase	PMID: 18776219 PMID: 23029125