Table 3.

Independent association of physical function, gout and hyperuricemia in older adults

	Grip strength (kg)	SPPB score	Walking speed (m/s)
Adjusted mean difference in physical function
No gout (n=5,224)	Reference	Reference	Reference
Gout (n=595)	−0.09 (−0.70, 0.52)	0.77 (0.65, 0.90)	−0.03 (−0.05, −0.01)
P-value	0.77	0.001	<0.001
No hyperuricemia (n=4,577)	Reference	Reference	Reference
Hyperuricemia (n=1,242)	−0.05 (−0.52, 0.43)	0.87 (0.77, 0.98)	−0.02 (−0.03, −0.005)
P-value	0.85	0.02	0.01
Poor physical function
No gout (n=5,224)	Reference	Reference	Reference
Gout (n=595)	1.04 (0.92, 1.18)	1.18 (1.07, 1.32)	1.19 (1.06, 1.34)
P-value	0.49	0.002	0.003
No hyperuricemia (n=4,577)	Reference	Reference	Reference
Hyperuricemia (n=1,242)	0.98 (0.89, 1.07)	1.09 (1.00, 1.19)	1.11 (1.00, 1.22)
P-value	0.60	0.048	0.04

All models were adjusted for: Age, sex, race, BMI, smoking status, hypertension, stroke, diabetes, CHD, osteoarthritis, kidney function, and alcohol intake. The measure of associations for poor physical function are prevalence ratios.

Ordinal logistic regression was used for SPPB score

For all three measures of physical function greater values are indicative of better function.

Low physical function was defined as the lowest quartile for grip strength (≤22 kg), SPPB (≤7) and walking speed (≤0.76 m/s).

Sample sizes for walking speed are listed in Table 1 footnotes.