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. Author manuscript; available in PMC: 2016 Jan 3.
Published in final edited form as: AJR Am J Roentgenol. 2012 May;198(5):W432–W439. doi: 10.2214/AJR.11.7367

TABLE 1.

Summary of Demographics, Joint and Regional Bone Involvement, and Outcomes of 20 Patients With Described Signal Abnormalities

Patient
No., Study		 Sex Age (y) at First
MRI
Examination		 Time Between
Diagnosis and
First MRI
Examination
(mos)		 Time Between First
and Second MRI
Examination (mos)		 Time Between
Diagnosis and Follow-Up
Examination (mos)		 Joint Epiphyseal Metaphyseal Diaphyseal Unilateral vs
Bilateral		 Outcome
≥ 30% < 30% None
1 Male 12.2 5.1 13.8 90.7 Knees
  MRI 1 Positive Negative Negative Positive Positive Bilateral
  MRI 2 Positive Negative Negative Positive Positive Bilateral Stable osteonecrosis
1 Male 12.2 5.1 13.8 90.7 Hips
  MRI 1 Positive Negative Negative Negative Negative Bilateral Extensive osteonecrosis with collapse
  MRI 2 Positive Negative Negative Positive Positive Bilateral Total hip replacement
2 Male 14 6.2 1.6 73.5 Knees
  MRI 1 Positive Negative Negative Positive Negative Bilateral
  MRI 2 Positive Negative Negative Positive Positive Bilateral Extensive osteonecrosis with partial collapse
3 Male 13.4 5.8 3.3 31.6 Knees
  MRI 1 Negative Negative Positive Positive Negative Bilateral
  MRI 2 Negative Positive Negative Positive Positive Bilateral Extensive osteonecrosis
4 Female 11.9 4.4 2.8 48.3 Knees
  MRI 1 Positive Negative Negative Positive Negative Bilateral
  MRI 2 Positive Negative Negative Positive Positive Bilateral Extensive osteonecrosis
5 Female 14.9 3 2.5 2.5 Knees
  MRI 1 Positive Negative Negative Positive Negative Bilateral
  MRI 2 Positive Negative Negative Positive Negative Bilateral Stable osteonecrosis
6 Male 18 8.3 18.5 19.3 Knees
  MRI 1 Positive Negative Negative Positive Negative Bilateral
  MRI 2 Positive Negative Negative Positive Positive Unilateral Extensive osteonecrosis
7 Male 19.2 5.7 3.6 33.1 Knees
  MRI 1 Negative Negative Positive Positive Positive Bilateral
  MRI 2 Positive Negative Negative Positive Positive Bilateral Extensive osteonecrosis with collapse
8 Female 11 5.9 3 25 Knees
  MRI 1 Positive Negative Negative Positive Negative Bilateral
  MRI 2 Positive Negative Negative Positive Negative Bilateral Stable osteonecrosis
9 Male 17 6 3.2 38.8 Knees
  MRI 1 Positive Negative Negative Positive Negative Bilateral
  MRI 2 Positive Negative Negative Positive Negative Bilateral Stable osteonecrosis with collapse
10 Female 11.3 5.9 3.2 37.6 Knees
  MRI 1 Positive Negative Negative Positive Positive Bilateral
  MRI 2 Positive Negative Negative Positive Positive Bilateral Stable osteonecrosis
11 Male 15.2 7.5 3.2 23.5 Knees
  MRI 1 Negative Positive Negative Positive Positive Bilateral
  MRI 2 Negative Positive Negative Positive Positive Bilateral Stable osteonecrosis
12 Female 15.8 5.9 2.5 24.9 Knees
  MRI 1 Positive Negative Negative Negative Negative Unilateral
  MRI 2 Positive Negative Negative Positive Positive Bilateral Extensive osteonecrosis
13 Male 16.7 5.8 3 31.1 Knees
  MRI 1 Negative Positive Negative Negative Negative Bilateral
  MRI 2 Positive Negative Negative Positive Positive Bilateral Extensive osteonecrosis
14 Male 11.8 7 3.9 15.8 Knees
  MRI 1 Positive Negative Negative Positive Negative Bilateral
  MRI 2 Positive Negative Negative Positive Negative Bilateral Stable osteonecrosis
15 Female 10.3 6.3 2.5 8.7 Knees
  MRI1 Negative Positive Negative Positive Positive Bilateral
  MRI2 Positive Negative Negative Positive Positive Bilateral Extensive osteonecrosis
15 Female 10.3 6.3 2.5 8.7 Hips
  MRI 1 Negative Positive Negative Positive Positive Bilateral Extensive osteonecrosis with collapse
  MRI 2 Positive Negative Negative Positive Positive Bilateral Right hip core decompression
16 Female 12 5.9 3.4 3.4 Knees
  MRI 1 Positive Negative Negative Positive Negative Bilateral
  MRI 2 Positive Negative Negative Positive Positive Bilateral Extensive osteonecrosis
17 Male 8.7 7 1.9 1.9 Knees
  MRI 1 Positive Negative Negative Positive Positive Bilateral
  MRI 2 Positive Negative Negative Positive Positive Bilateral Stable osteonecrosis
18 Male 4.1 6.5 2.8 32 Knees
  MRI 1 Negative Negative Positive Positive Negative Unilateral
  MRI 2 Negative Negative Positive Positive Negative Unilateral Stable osteonecrosis
19 Male 12.7 6 2.5 2.5 Knees
  MRI 1 Negative Positive Negative Positive Positive Bilateral
  MRI 2 Positive Negative Negative Positive Positive Bilateral Extensive osteonecrosis
20 Female 17.7 6 2.3 7 Knees
  MRI 1 Positive Negative Negative Positive Positive Bilateral
  MRI 2 Positive Negative Negative Positive Positive Bilateral Stable osteonecrosis
20 Female 17.7 6 2.3 7 Hips
  MRI 1 Negative Negative Positive Negative Positive Bilateral
  MRI 2 Negative Positive Negative Negative Positive Bilateral Extensive osteonecrosis