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. Author manuscript; available in PMC: 2016 Jan 3.
Published in final edited form as: Am J Surg Pathol. 2015 Jan;39(1):25–34. doi: 10.1097/PAS.0000000000000343

Table 2. Comparison of bISH for albumin, Hep Par1 and Arginase for the diagnosis of hepatocellular carcinoma.

ALBUMIN + HEP PAR1+ ARGINASE+
N=93 N=89 N=87
%+ Score0 Score1 Score2 Score3 %+ Score0 Score1 Score2 Score3 %+ Score0 Score1 Score2 Score3
All cases 99% 1 0 3 89 84% 14 7 8 60 83% 15 11 18 43
Grade 1 100% 0 0 0 6 100% 0 0 0 4 100% 0 1 2 1
Grade 2 100% 0 0 1 50 98% 1 5 4 39 90% 5 5 11 27
Grade 3 99% 1 0 2 33 64% 13 2 4 17 71% 10 5 5 15

Score 1=< 5% of tumor staining positive

Score 2=5% to 50% of tumor staining positive

Score 3> 50% of tumor staining positive

Albumin was evaluated using in situ hybridization

Hep Par1 and Arginase-1 was evaluated on an immunohistochemistry platform

Grade = grade of differentiation