Table 1.

Characteristics of gracilis muscle arterioles and blood pressure of mice

	M-WT	F-WT	M-KO	F-KO
n	6–8	8	6–12	6–17
Diameter, μm
Active	90.1 ± 2.1+	98.2 ± 3.6	100.1 ± 3.3	100.5 ± 1.7
Passive	146.3 ± 2.2+	132.0 ± 3.3	137.9 ± 4.9	133.8 ± 3.2
Basal tone, %passive diameter	61.5 ± 1.1+	74.4 ± 1.6	72.8 ± 1.4	75.4 ± 1.1
Mean arterial blood pressure, mmHg	93.5 ± 0.2	84.5 ± 0.5*	83.2 ± 0.5*	78.5 ± 1.1*#

Values are means ± SE. F-KO, female soluble epoxide hydrolase knockout (sEH-KO) mice. +Significant difference from the other 3 groups of mice;

^*significant difference from male wild-type (M-WT);

^#significant difference from female wild-type (F-WT) and male sEH-KO (M-KO) mice.