Downstream gene targets of predicted cytokine and transcriptional regulators. Networks were generated using Ingenuity Pathway Analysis (IPA) for gene expression relative to non-IR control for day 1 (A), day 3 (B), day 7 (C), day 14 (D), or day 28 (E) after iron-IR. Gene expression signal is colored red (upregulated) or green (downregulated), while predicted upstream regulators have a larger font size and are colored orange (activated) or blue (inhibited).