Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
The release of sFlt-1 is greater under hypoxic conditions in placental villous explants isolated from obese MC4R+/− (n = 10) versus lean MC4R+/+ (n = 6) pregnant rats. Placental explant studies were conducted as previously described (55). The sFlt-1 was quantified using a mouse Flt-1 ELISA from R&D Systems. Data are means ± SE. *P < 0.05 vs. MC4R+/+ pregnant rats. These data are unpublished.
