Fig. 6.

TRPV3 channel activation dilates cerebral PA. A: representative recording of a pressurized PA after exposure to carvacrol (10 μM) or IPP (3 μM) + carvacrol. B: summary data of the change in PA diameter (Δdiameter) after exposure to carvacrol in the absence and presence of isopentenyl pyrophosphate (IPP; n = 5). C: IPP had no effect on basal myogenic tone of cerebral PA (n = 5). D: removal of the endothelium almost completely abolished carvacrol-induced dilation of PAs (n = 6). *P ≤ 0.05 vs. carvacrol.