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. 2015 Oct 9;309(12):H2077–H2086. doi: 10.1152/ajpheart.00685.2015

Table 4.

Twitch characteristics of muscle utilized for ktr experiments

Fdev,mN/mm2 Frest, mN/mm2 TTP, ms +dF/dt mN·mm−2·s−1 +dF/dt/F, s−1 RT50, ms −dF/dt, mN·mm−2·s−1 −dF/dt/F, s−1
Nonfailing
    Lopt 23.2 ± 1.7 7.5 ± 0.7 212.6 ± 12.1 179.8 ± 16.6 7.8 ± 0.5 137.0 ± 4.0 −127.6 ± 9.1 −5.5 ± 0.2
    L95 9.3 ± 1.1* 4.2 ± 0.5* 174.7 ± 8.7* 84.8 ± 11.8* 9.0 ± 0.5* 123.9 ± 5.6* −51.8 ± 5.4* −5.7 ± 0.2
    L90 4.9 ± 0.6* 2.4 ± 0.3* 155.4 ± 7.1* 48.6 ± 8.1* 9.5 ± 0.7* 114.7 ± 5.3* −30.8 ± 3.7* −6.3 ± 0.3*
    Lopt,repeat 8.9 ± 1.1* 6.8 ± 0.8 181.0 ± 8.7* 79.1 ± 12.1* 8.6 ± 0.5* 126.7 ± 3.7 −49.0 ± 5.7* −5.6 ± 0.2
Failing
    Lopt 18.5 ± 3.0 10.6 ± 1.6 181.0 ± 10.8 154.8 ± 21.0 8.8 ± 0.5 136.4 ± 5.9 −96.6 ± 15.3 −5.3 ± 0.2
    L95 10.8 ± 2.3* 5.7 ± 1.4* 159.3 ± 8.8* 96.7 ± 17.2* 9.6 ± 0.5* 120.4 ± 4.4* −59.8 ± 12.9* −5.5 ± 0.2
    L90 7.3 ± 1.7* 3.7 ± 1.8* 147.7 ± 8.3* 71.7 ± 14.1* 10.4 ± 0.5* 109.8 ± 2.7* −43.8 ± 9.3* −6.3 ± 0.3*
    Lopt,repeat 14.9 ± 3.4 10.6 ± 2.6 177.3 ± 10.5 127.6 ± 27.3 8.9 ± 0.5 126.0 ± 6.1 −78.9 ± 17.7 −5.3 ± 0.3

All parameters were means ± SE (measured at 1 Hz); n = 9 nonfailing, n = 10 failing (1 trabecula/heart). Fdev, active developed force (i.e., total minus resting); Frest, resting force (lowest force during a twitch); +dF/dt/F, maximal velocity of contraction normalized to active developed force; −dF/dt/F, maximal velocity of relaxation normalized to active developed force. P < 0.05 as determined with ANOVA for repeated measures with Bonferroni post hoc analysis:

*

vs. Lopt,

vs. L95,

vs. Lopt,repeat of the same group.