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Initial and pressor slope responses of hindlimb vascular resistance during muscle metaboreflex activation (n = 6) in control (open bars), after α1-blockade (hatched bars), β-blockade (cross-hatched bars), and α1 + β-blockade (solid bars). *P ≤0.05 vs. the initial slope; †P ≤ 0.05 vs. the control setting.
