. 2015 Oct 16;309(12):H2145–H2151. doi: 10.1152/ajpheart.00679.2015

Table 1.

Mean hemodynamic values during rest, free-flow exercise, and MMA during control experiments and after α₁-blockade, β-blockade, and α₁ + β-blockade

	Control	α₁-Blockade	β-Blockade	α₁ + β-Blockade
Mean arterial pressure, mmHg
Rest	88.4 ± 1.9	81.4 ± 1.4^†	84.4 ± 2.2	76.9 ± 2.0^†
Exercise	92.1 ± 1.2^*	83.5 ± 1.6^*^†	90.3 ± 3.5^*	81.5 ± 1.9^†
MMA	143.6 ± 1.6^*	119.5 ± 3.4^*^†	114.4 ± 5.4^*^†	113.7 ± 4.8^*^†
Cardiac output, l/min
Rest	2.75 ± 0.15	2.87 ± 0.18	2.59 ± 0.10	2.70 ± 0.16
Exercise	4.32 ± 0.23^*	4.48 ± 0.21^*	3.71 ± 0.25^*^†	4.03 ± 0.24^*
MMA	6.50 ± 0.27^*	6.66 ± 0.21^*	4.11 ± 0.23^*^†	4.71 ± 0.32^*^†
Heart rate, beats/min
Rest	69.9 ± 4.2	83.2 ± 5.5^†	70.4 ± 3.1	80.3 ± 4.4
Exercise	101.0 ± 2.8^*	112.9 ± 4.8^*^†	95.3 ± 1.0^*^†	106.6 ± 4.7^*
MMA	141.0 ± 3.6^*	159.4 ± 8.6^*^†	104.3 ± 4.3^†	119.6 ± 6.7^*^†
Nonischemic vascular conductance, ml·min⁻¹·mmHg⁻¹
Rest	24.3 ± 1.3	28.1 ± 2.2^†	24.6 ± 1.2	27.9 ± 1.8^†
Exercise	34.2 ± 1.7^*	39.6 ± 2.6^*^†	29.7 ± 1.3^*^†	36.3 ± 1.7^*
MMA	41.4 ± 1.7^*	50.8 ± 1.7^*^†	31.5 ± 1.3^†	36.4 ± 1.9^†
Hindlimb blood flow, l/min
Rest	0.60 ± 0.07	0.60 ± 0.04	0.52 ± 0.05	0.55 ± 0.04
Exercise	1.18 ± 0.13^*	1.20 ± 0.09^*	1.02 ± 0.12^*^†	1.07 ± 0.13^*
MMA	0.55 ± 0.04	0.64 ± 0.05^†	0.52 ± 0.04	0.56 ± 0.04

Values are means ± SE; n = 6 animals. MMA, maximal metaboreflex activation.

P < 0.05 vs. previous setting in same experiment;

^†

P< 0.05 vs. control settings.