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editorial
. 2016 Jan 7;22(1):1–7. doi: 10.3748/wjg.v22.i1.1

Table 1.

MiRNAs and their targets in esophageal cancer

miRNA Expression profile ESCC EAC Related biological function Ref.
miRNA-21 PTEN Cell proliferation [8,17,18]
PDCD4 Cell migration, apoptosis [9]
Let-7 HMGA2 Cell proliferation [25,26]
IL-6 Cytokine activity [27]
miRNA-143 and -145 FSCN FSCN Cell migration [29,32]
ERK5 Cell proliferation, cell migration [30]
miRNA-196a Annexin A1 Apoptosis [38,39]
SPRR2C Pseudogene [38]
S100A9 Cell differentiation, cell proliferation [38]
KRT5 Cell architecture [38]
RAP1A Cell proliferation, cell adhesion and cell migration [41]

miRNAs with corresponding expression profile (↑ = upregulated, ↓ = downregulated in esophageal cancer), described targets and related biological function in esophageal squamous cells carcinoma (ESCC) and esophageal adenocarcinoma (EAC).