Table 2.
Low-grade non-Hodgkin’s lymphoma.
| Sub-type | Cell type |
|---|---|
| Follicular lymphoma (25%) | B-type |
| Mantle cell lymphoma (5-10%) | B-type |
| Marginal zone lymphoma (12%) | Gastric MALT, small bowel, salivary, thyroid, tear glands, lungs, etc. |
| Extranodal (mucosa associated lymphoid tissue-MALT) (9%) | B-type, it occurs within the lymph nodes |
| Nodal marginal zone lymphoma (monocytoid B cell lymphoma) (2%) | B-type, it starts in the spleen and can also be found in the bloodstream (villous lymphocytes); over age 50; allelic loss at the 7q chromosomal region; indolent but small subset it follows an aggressive course |
| Splenic marginal zone lymphoma (primary splenic lymphoma) (1%) | |
| Small lymphocytic lymphoma (CLL)(6%) | Leukemia and lymphoma have many similarities: |
| CLL - many of the abnormal cells are in the blood | |
| Small lymphocytic lymphoma - involves the lymph nodes in particular | |
| Lymphoplasmacytic lymphomas | Blood thicker - high level of immunoglobulin M |
| (Waldenstrom’s macroglobulinemia or immunocytoma) (2%) | Abnormal B cells fill up the bone marrow or enlarge the lymph nodes or spleen |
| Skin lymphomas (mycosis fungoides) | Rare NHL type (CD30 cutaneous T cell) lymphoma |
MALT, mucosa-associated lymphoid tissue-type; CLL, chronic lymphocytic leukemia; NHL, non-Hodgkin’s lymphoma.