Table 3.
High-grade non-Hodgkin’s lymphoma.
| Diffuse large B cell lymphoma Mediastinal (thymic) large B cell lymphoma (3%) | Most common (30%), occur any age, mostly mid to late 60’s tends to occur in people in their 20s and 30s |
| Burkitt’s lymphomas (3%) | Malignant B cells (30-50% of childhood lymphoma) Endemic variant (chronic malaria reduce resistance to Epstein-Barr virus, jaw commonly involved) Immunodeficiency-associated (post-transplant, AIDS) Sporadic type (ileo-caecal) |
| PTCL (6%) | It develops from mature T cells |
| PTCL not otherwise specified | |
| ALCL | It can occur also in the liver, bone marrow, digestive system and skin |
| AITL | |
| ALCL (2%) | It occurs most commonly in children and young adults; more common in males than females; it appears in the skin, in lymph nodes, or in organs throughout the body; several different subtypes with different outcomes and treatment options |
| AITL (2%) | Quickly growing T cell lymphoma |
| Lymphoblastic lymphoma (2%) | T cells, but occasionally it develops from B cells Under the age of 35, very rare in adults and most common in children and teenagers Lymphoblastic lymphoma is very similar to ALL. In lymphoma, the abnormal lymphocytes are generally in the chest lymph nodes or thymus gland but in ALL the abnormal cells are mainly in the blood and bone marrow. Similar treatments for lymphoblastic lymphoma and ALL |
| Blastic natural killer-cell lymphoma | Very rare type of T cell lymphoma; it affects only a few people each year; usually it occurs in adults, grow very quickly and can be difficult to treat; it can start almost anywhere in the body |
| Enteropathy associated T cell lymphoma or intestinal T cell lymphoma | Usually it occurs in the small bowel (jejunum or the ileum); celiac disease; 30s and 40s; it may spread to the liver, spleen, lymph nodes, gallbladder, stomach, colon or skin and tends to grow very quickly; Crohn’s disease with suppressed immune system |
PTCL, peripheral T cell lymphomas; ALCL, anaplastic large cell lymphoma; AITL, angio-immunoblastic T cell lymphoma; ALL, acute lymphoblastic leukemia.