Figure 1. Structural architecture of the SaNSR monomer.

(a) Schematic illustration of the domain organization of SaNSR indicating the domain borders and catalytically important residues (His₉₈ and Ser₂₃₆). (b) The overall structure of a SaNSR monomer in a cartoon representation. The N-terminal helical bundle is depicted in green where the light green region represents the N-pep. The protease cap and core domains are highlighted in red and grey, respectively. The catalytically important residues and the highly conserved “TASSAEM” region are depicted in blue.