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. 2016 Jan 4;6:18669. doi: 10.1038/srep18669

Figure 2. EMT scores and influence of mutations on survival.

Figure 2

(A) Distribution of EMT scores in different tumor types in the pan-cancer gene expression dataset. Boxplots show mean and SEM with whiskers indicating 1–99th percentile. P-values indicate significance of difference in means from Tukey’s HSD post-hoc analysis (following one-way ANOVA). (B) EMT score as a metric for metastatic potential and impact on patient survival rates. Kaplan-Meier survival curve for the pan-cancer patient tumors stratified according to Low EMT (< Avg. EMT score) or High EMT (≥ Avg. EMT score). Kaplan-Meier survival curve for pan-cancer tumors stratified by the mutation status of (C) TP53 and (D) STK11. (B–D). P-value indicates significance levels from the comparison of survival curves using the Log-rank (Mantel-Cox) test.