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. 2016 Jan 4;6:18669. doi: 10.1038/srep18669

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Copyright © 2016, Macmillan Publishers Limited

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(A) Bar graph showing average SCO2 expression levels in tumors loss or gain in copy number compared to somatic levels in the pan-cancer dataset. (B) Bar graph showing average expression of SCO2 in context of p53 mutation background. P-values in (A,B) indicate significance level from one-way ANOVA. (C) Kaplan-Meier survival curves indicating the influence of tumor stratification on the basis of low (n = 4366) or high (n = 3025) SCO2 expression in the pan-cancer dataset. (D) Kaplan-Meier survival curves showing the influence of wild-type p53 and low SCO2 expression (n = 1561), wild-type p53 with high SCO2 expression or mutant p53 with low SCO2 expression (n = 1269), and mutant p53 with high SCO2 expression (n = 495) on the survival rates in the pan-cancer dataset. P-values in (C,D) indicate significance levels from the comparison of survival curves using the Log-rank (Mantel-Cox) test.