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. 2015 Nov 18;29(1):1–15. doi: 10.5713/ajas.16.0001R

Table 1.

Summary of physiological roles of adipokines, hepatokines and myokines in ruminants

Physiological roles
Adipokines Leptin Correlated with BCS and carcass composition
Decreased the GH secretion
Adiponectin Increased after parturition
Increased gene expression of adipose tissue in lactating cows
TNF-α Increased TG
Increased lipolysis
Chemerin Increased insulin secretion
Hepatokines IGFs Increased milk production
Correlated with growth
Selenoprotein P Increased gene expression by insulin
Chemerin Decreased in the liver of post-weaning calves
Decreased the gene expression by insulin and propionate
ANGPTL8 Decreased after parturition
FGF21 Increased after parturition
Myokines IL-6 Adipose tissue oxidation
Anti-inflammation
BDNF Myogenesis
Irisin High expression in skeletal muscle
HGF Muscle regeneration
Sema3A Muscle hypertrophy

TNF-α, tumor necrosis factor-α; IGFs, insulin like growth factors; ANGPTL8, angiopoietin-like protein 8; FGF21, fibroblast growth factor 21; IL-6, interleukin- 6; BDNF, brain-derived neurotropic factor; HGF, hepatocyte growth factor; Sema3A, semaphorin 3A.