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. 2016 Jan 4;6:18766. doi: 10.1038/srep18766

Table 2. Summary risk estimates of the association between ever parity and gastric cancer risk.

  No. of Study SRR 95% CI I2 (%) Ph Ph
Overall 7 0.96 0.87–1.05 0 0.504  
Subgroup analyses            
Number of cases           0.383
 ≥250 3 0.96 0.85–1.08 15.1 0.317  
 <250 4 0.84 0.62–1.13 0 0.594  
Follow-up years           0.974
 ≥10 2 0.90 0.87–1.05 42.4 0.176  
 <10 5 0.94 0.81–1.11 0 0.593  
Geographic location           0.221
 Europe 3 0.98 0.89–1.08 0.8 0.388  
 Asia 3 0.80 0.58–1.12 0 0.517  
 North America 1 0.76 0.44–1.31 N/A N/A  
Menopausal status           0.962
 Pre-menopausal 1 0.83 0.65–1.05 N/A N/A  
 Post-menopausal 3 0.83 0.61–1.13 66.7 0.029  
Anatomic subsite           0.279
 Cardia 2 0.81 0.61–1.07 1.2 0.314  
 Non-cardia 3 0.99 0.88–1.12 0 0.589  
Adjustment for potential confounders and risk factors
Age           0.769
 Yes 5 0.95 0.82–1.10 0 0.862  
 No 2 0.82 0.59–1.15 60.0 0.082  
Cigarette smoking           0.974
 Yes 5 0.95 0.81–1.11 0 0.593  
 No 2 0.90 0.72–1.12 42.4 0.176  
Body mass index           0.617
 Yes 4 0.97 0.82–1.14 0 0.827  
 No 3 0.85 0.68–1.08 44.3 0.146  
Alcohol drinking           0.844
 Yes 3 0.88 0.67–1.15 24.6 0.265  
 No 4 0.97 0.86–1.08 0 0.468  
Socioeconomic status           0.340
 Yes 5 0.97 0.87–1.07 3 0.397  
 No 2 0.81 0.58–1.12 0 0.774  

CI, confidence interval; N/A, not available; SRR, summarized relative risk.

P-value for heterogeneity within each subgroup.

P-value for heterogeneity between subgroups with meta-regression analysis.