Table 3.
Transcripts commonly and uniquely differentially expressed in response to asbestos exposure. A) Transcripts known to be involved with MM that were significantly differentially expressed in all cell lines, and B) Transcripts uniquely differentially expressed between pleural and peritoneal mesothelial cells. These transcripts represent the interaction between Cell Source and Treatment ((p<0.05, FDR<0.05, 2X fold change).
| A. | |||||
|---|---|---|---|---|---|
| RefSeq ID | Gene symbol |
HPM3 Fold Change |
HPM4 Fold Change |
HM3 Fold Change |
LP9 Fold Change |
| NM_000584 | IL8 | 33.523 | 68.4999 | 12.6472 | 13.3992 |
| NM_001145033 | C11orf96 | 15.5014 | 68.4658 | 21.0523 | 2.87073 |
| NM_002089 | CXCL2 | 8.59856 | 59.7874 | 11.2084 | 4.85504 |
| NM_002090 | CXCL3 | 5.8495 | 57.1446 | 12.237 | 3.08622 |
| NM_004591 | CCL20 | 2.6658 | 41.6213 | 9.11657 | 1.69404 |
| NM_000600 | IL6 | 7.55715 | 34.5214 | 10.7801 | 1.97597 |
| NM_001030287 | ATF3 | 12.0644 | 31.31 | 25.8987 | 7.32549 |
| NM_001130046 | CCL20 | 4.0348 | 27.2693 | 6.23303 | 2.24153 |
| NM_015714 | G0S2 | 9.33613 | 20.1768 | 6.38625 | 1.79726 |
| NM_001206486 | ATF3 | 4.95986 | 17.7409 | 10.1859 | 5.9077 |
| NM_001674 | ATF3 | 2.88467 | 11.3234 | 7.8942 | 4.45283 |
| NM_173157 | NR4A1 | 9.26958 | 9.28196 | 6.07496 | 2.36559 |
| B. | |||
|---|---|---|---|
| RefSeq ID | Gene symbol | HMP3 vs. HM3 Fold Change |
HMP4 vs. HM3 Fold Change |
| NM_001145033 | C11orf96 | 2.1016 | 1.16537 |
| NM_004591 | CCL20 | 3.95134 | 1.84928 |
| NM_001130046 | CCL20 | 2.59972 | 1.24291 |
| NM_000758 | CSF2 | 3.37437 | 1.85269 |
| NM_172219 | CSF3 | 6.99657 | 3.669 |
| NM_000759 | CSF3 | 4.62554 | 2.09011 |
| NM_001178147 | CSF3 | 3.76625 | 2.13401 |
| NM_172220 | CSF3 | 3.21695 | 1.87829 |
| NR_033662 | CSF3 | 2.77213 | 1.67068 |
| NM_002089 | CXCL2 | 2.63689 | 1.14172 |
| NM_002090 | CXCL3 | 3.12556 | 1.44637 |
| NM_013409 | FST | 2.60138 | 2.01464 |
| NM_001191322 | GREM1 | 2.04879 | 1.78317 |
| NM_013372 | GREM1 | 1.78934 | 2.09912 |
| NM_000575 | IL1A | 4.64077 | 1.92285 |
| NM_000576 | IL1B | 3.84257 | 1.85831 |
| NM_000600 | IL6 | 2.1373 | 1.19435 |
| NM_001256339 | NKX3-1 | 2.19502 | 1.76747 |
| NM_006167 | NKX3-1 | 2.6504 | 1.27087 |
| NR_046072 | NKX3-1 | 2.29697 | 1.35888 |
| NM_002638 | PI3 | 2.14985 | 1.36983 |
| NM_003713 | PPAP2B | 2.65004 | 1.68872 |
| NM_000963 | PTGS2 | 2.27583 | 1.22729 |
| NM_002852 | PTX3 | 2.12739 | 1.05261 |
| NM_016321 | RHCG | 2.02976 | 1.27926 |
| NM_007115 | TNFAIP6 | 2.03878 | 1.40361 |
| NM_014350 | TNFAIP8 | 2.17025 | 1.30366 |
| NM_001190947 | TRAF1 | 2.03622 | 1.15353 |
| NM_006022 | TSC22D1 | 2.37599 | 1.75202 |