Table 2.

Genotype frequency distributions of 1513A>C and -762T>C in P2X7 gene.

Genotype	Control group (n = 87)	Case group (n = 103)	P	OR	95% CI
1513A>C
AA	51 (58.6%)	33 (32.0%)	Ref.
AC	27 (31.0%)	49 (47.6%)	0.002	2.805	1.475–5.332
CC	9 (10.4 %)	21 (20.4%)	0.004	3.606	1.473–8.829
Dominant model
AA	51 (58.6%)	33 (32.0%)	Ref.
AC + CC	36 (41.4%)	70 (67.6%)	<0.001	3.005	1.658–5.446
Recessive model
AA + AC	78 (89.6%)	82 (79.6%)	Ref.
CC	9 (10.4%)	21 (20.4%)	0.06	2.22	0.958–5.143
Allele
A	129 (74.1%)	115 (55.8%)	Ref.
C	45 (25.9%)	91 (44.2%)	<0.001	2.268	1.466–3.511
-762T>C
TT	48 (55.2%)	21 (20.4%)	Ref.
TC	30 (34.5%)	47 (45.6%)	<0.001	3.581	1.800–7.123
CC	9 (10.3%)	35 (34.0%)	<0.001	8.889	3.634–21.74
Dominant model
TT	48 (55.2%)	21 (20.4%)	Ref.
CC + TC	39 (44.8%)	82 (79.6%)	<0.001	4.932	2.598–9.365
Recessive model
TT + TC	78 (89.7%)	68 (66.0%)	Ref.
CC	9 (10.3%)	35 (34.0%)	<0.001	4.461	2.001–9.944
Allele
T	126 (72.4%)	89 (43.3%)	Ref.
C	48 (27.6%)	117 (56.8%)	<0.001	3.451	2.240–5.315

OR: odds ratio; CI: confidence interval; Ref.: reference.