Figure 3.

225THC modulates inflammatory cytokine and chemokine responses in murine BV2 microglial cells. 225THC-modulation of cytokine/chemokine secretion by the BV2 microglial cell line. ELISA assessment of cytokine ((a) TNF-α) and chemokine ((b) MCP-1; (c) RANTES; (d) MIP) secretion by BV2 microglial cells following stimulation with LPS (2 μg/mL) for 24 h in the presence of 225THC at the concentrations indicated. Statistical analysis was performed by a two-way ANOVA with Bonferroni post hoc analysis; ∗ indicates p < 0.05, ^∗∗ p < 0.01; ns, not significant when compared with basal or as indicated.