Fig 3. A network of S. Typhi protein-protein interactions predicted by our method, where prediction score > 2 and average GO semantic similarity score > 0.7.

The network was construct by Cytoscape 3.2.1 [25]. Each node of the network represents S. Typhi protein. The green edges of network represent the validated protein-protein interactions of S. Typhi by STRING database, where confidence score > 0.7 [15]. Interacting proteins of STRING database (experimental PPIs only) were denoted by pink nodes.