Figure 3.

Anti-inflammatory effect of genipin + glycine blue pigment on edema in mice. Maximum edema depression was observed 1 h after edema induction. Notably, treatment with blue pigments at 120 mg/kg reduced edema by ca. 22% (from ca. 60% to 38%) at 1 h, whereas the positive control, dexamethasone (10 mg/kg) depressed the edema by ca. 35% at 1 h. The data are indicative of the safety of genipin which alleviates inflammation by exerting biochemical actions favorable to the organism. Reproduced from [33].