Table 3.
Acid–base parameters and electrolytes before and after ECAD
| MARS, median (IQR) | SPAD, median (IQR) | |||||
|---|---|---|---|---|---|---|
| Pre-ECAD | Post-ECAD | Difference | Pre-ECAD | Post-ECAD | Difference | |
| pH | 7.42 (7.374–7.447) | 7.42 (7.390–7.449) | n.s. | 7.40 (7.356–7.424) | 7.43 (7.386–7.454) | * |
| SBC, mmol/L | 27.3 (24.03–31.48) | 27.5 (24.70–30.60) | n.s. | 25.1 (22.75–27.50) | 27.8 (24.45–30.60) | * |
| Base excess, mmol/L | 3.9 (0.03–8.35) | 3.8 (0.70–7.20) | n.s. | 1.3 (−1.40/+3.85) | 4.0 (0.40/7.65) | * |
| Lactate, mmol/L | 1.9 (1.30–2.70) | 2.1 (1.70–3.00) | * | 1.8 (1.30–2.75) | 2.5 (1.70–3.60) | *,** |
| Sodium, mmol/L | 142 (138.3–146.0) | 143 (139.0–147.0) | n.s. | 141 (136.5–146.0) | 144 (139.0–148.5) | *,** |
| Potassium, mmol/L | 4.5 (4.20–4.70) | 4.2 (3.90–4.60) | * | 4.4 (4.15–4.70) | 4.2 (3.90–4.60) | * |
| Calcium, mmol/L | 1.24 (1.140–1.330) | 1.15 (1.090–1.260) | * | 1.21 (1.115–1.310) | 1.06 (0.890–1.145) | *,** |
| Glucose, mmol/L | 6.9 (5.70–8.00) | 7.3 (6.15–8.05) | n.s. | 6.6 (6.00–7.80) | 7.5 (6.50–8.80) | * |
| Osmolality, mOsmol/kg H2O | 305.1 (295.85–320.79) | 305.7 (297.24–319.79) | n.s. | 304.5 (294.53–312.01) | 310.1 (299.76–319.85) | *,** |
ECAD extracorporeal albumin dialysis, MARS Molecular Adsorbents Recirculating System, SPAD single-pass albumin dialysis, SBC standard bicarbonate, IQR interquartile range, n.s. non-significant
*p < 0.05 significant changes within ECAD
**p < 0.05 significant differences between both devices