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. Author manuscript; available in PMC: 2016 Jan 4.
Published in final edited form as: Gene Ther. 2013 Nov 21;21(2):148–157. doi: 10.1038/gt.2013.67

Figure 3.

Figure 3

High GFP-positive rates in granulocytes and monocytes at 1–2 months after RIC HSC transplantation. (a) At 2 weeks after transplantation in both animals, we observed ~2% of GFP-positive rates (%GFP) in RBCs, but undetectable in granulocytes, lymphocytes, monocytes or platelets. %GFP in RBCs gradually decreased and was undetectable by 3 months. Interestingly, %GFP in granulocytes and monocytes were unexpectedly high (80–99%) starting at 1–2 months after transplantation, and declined to undetectable levels by 3–4 months. (b) In lineage marker specific analysis (CD3, CD20, CD33, CD41a and RBC-specific antibodies), similar patterns were observed.