Skip to main content
. Author manuscript; available in PMC: 2016 Jan 4.
Published in final edited form as: Toxicol Sci. 2011 Oct 14;125(1):105–115. doi: 10.1093/toxsci/kfr271

FIG. 4.

FIG. 4

Effect of prior dermal exposure on airway responses induced by pulmonary exposure to furfuryl alcohol. Airway hyperreactivity (A), IgE (B), eosinophils (C), and neutrophils (D) were evaluated in mice dermally sensitized to furfuryl alcohol (25–75%) and challenged with furfuryl alcohol (2%; four doses) via the airways. Mice were sensitized with furfuryl alcohol (25, 50, or 75%) on days 1–4 of the experiment and then challenged with 2% furfuryl alcohol via pharyngeal aspiration on days 5, 9, 13, and 17. Error bars represent mean ± SE of seven mice per group. Statistical significance is designated as †p ≤ 0.01 as compared with the 2% furfuryl alcohol pulmonary exposure control (four doses) or *p ≤ 0.01 as compared with the vehicle control.