Table 1.
Mean survival of rats on the various diets used in this study and the number of DE genes compared with AL feeding
| Rat cohortsa | Mean survival (days) from [10] | SE (days) | Number of DE genes compared with AL |
|---|---|---|---|
| AL | 854 | 22 | NA |
| *AL > CR | 1000 | 33 | 1028 |
| AL + LA > CR | 859 | 57 | 986 |
| *CR | 1025 | 25 | 941 |
| CR > AL | 914 | 44 | 1435 |
| *CR > AL + LA | 1009 | 34 | 1233 |
| AL + LA | 858 | 27 | 1003 |
aDiet switches are indicated by “>” and occurred at 12 months of age. Asterisks (*) indicate long-lived cohorts, all statistically significant versus AL. Benjamini-Hochberg false discovery rate <0.05; n = 6 per group (pooled two by two) for the RNA-seq; 10,620 genes expressed in total. NA not applicable, SE standard error