Table 3.
Shared chromatin related and epigenetic regulator genes altered by CR and LA feeding
| Ensembl ID | Associated gene name | Description | AL versus CR log2 FC | AL versus CR FDR | AL versus AL+ LA log2 FC | AL versus AL+ LA FDR |
|---|---|---|---|---|---|---|
| ENSRNOG00000001442 | Por | NADPH--cytochrome P450 reductase [Source:UniProtKB/Swiss-Prot;Acc:P00388] | 1.24 | 8.58 × 10−06 | 0.75 | 1.19 × 10−02 |
| ENSRNOG00000043098 | Mt2A | Metallothionein-2 [Source:UniProtKB/Swiss-Prot;Acc:P04355] | 1.06 | 7.02 × 10−04 | 1.30 | 4.81 × 10−05 |
| ENSRNOG00000048961 | Bhlhe41 | Bhlhe41 | 1.06 | 5.45 × 10−04 | 0.92 | 7.17 × 10−03 |
| ENSRNOG00000047374 | Gnas | GNAS isoform GNASL [Source:RefSeq peptide;Acc:NP_062005] | 0.99 | 2.69 × 10−08 | 0.90 | 1.73 × 10−05 |
| ENSRNOG00000008001 | Rab3b | Ras-related protein Rab-3B [Source:UniProtKB/Swiss-Prot;Acc:Q63941] | 0.89 | 4.16 × 10−04 | 0.57 | 3.70 × 10−02 |
| ENSRNOG00000018958 | Mt3 | Metallothionein-3 [Source:UniProtKB/Swiss-Prot;Acc:P37361] | 0.77 | 3.94 × 10−03 | 0.58 | 3.88 × 10−02 |
| ENSRNOG00000005183 | Rtf1 | RNA polymerase-associated protein RTF1 homolog [Source:RefSeq peptide;Acc:NP_001102428] | 0.58 | 4.50 × 10−03 | 0.73 | 4.32 × 10−05 |
| ENSRNOG00000006816 | Urb5 | Ubiquitin protein ligase E3 component n-recognin 5 [Source:MGI Symbol;Acc:MGI:1918040] | −0.43 | 3.64 × 10−02 | −0.44 | 2.97 × 10−02 |
| ENSRNOG00000013837 | Trp53bp1 | Transformation related protein 53 binding protein 1 [Source:MGI Symbol;Acc:MGI:1351320] | −0.50 | 1.48 × 10−02 | −0.53 | 9.34 × 10−03 |
| ENSRNOG00000005544 | Kansl1 | KAT8 regulatory NSL complex subunit 1 [Source:MGI Symbol;Acc:MGI:1923969] | −0.53 | 2.46 × 10−02 | −0.61 | 1.26 × 10−02 |
| ENSRNOG00000004289 | Kdm6a | Lysine (K)-specific demethylase 6A [Source:MGI Symbol;Acc:MGI:1095419] | −0.59 | 1.24 × 10−02 | −0.55 | 7.33 × 10−03 |
| ENSRNOG00000003220 | H3f3c | Histone H3.3 [Source:UniProtKB/Swiss-Prot;Acc:P84245] | −0.72 | 4.50 × 10−02 | −0.75 | 1.50 × 10−02 |
| ENSRNOG00000011523 | H2afy | Core histone macro-H2A.1 [Source:UniProtKB/Swiss-Prot;Acc:Q02874] | −0.73 | 2.56 × 10−03 | −0.82 | 5.60 × 10−04 |
| ENSRNOG00000015781 | Ndst3 | Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3 [Source:RefSeq peptide;Acc:NP_001178645] | −0.82 | 4.27 × 10−03 | −0.77 | 8.10 × 10−03 |
| ENSRNOG00000046636 | HIST1H4B | Histone H4 Osteogenic growth peptide | −0.92 | 6.85 × 10−04 | -1.27 | 8.54 × 10−08 |
| ENSRNOG00000017714 | Usp3 | Ubiquitin carboxyl-terminal hydrolase 3 [Source:RefSeq peptide;Acc:NP_001020595] | −0.99 | 1.11 × 10−02 | −0.99 | 1.37 × 10−02 |
| ENSRNOG00000006689 | Chd7 | Chromodomain helicase DNA binding protein 7 [Source:MGI Symbol;Acc:MGI:2444748] | -1.09 | 3.92 × 10−03 | −0.93 | 1.60 × 10−02 |
| ENSRNOG00000014397 | Zic2 | zinc finger protein ZIC 2 [Source:RefSeq peptide;Acc:NP_001101862] | -1.81 | 5.00 × 10−04 | -2.06 | 7.44 × 10−05 |
Benjamini-Hochberg FDR <0.05; n = 6 per group (pooled two by two)