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. 2015 Dec 31;56(13):8428–8436. doi: 10.1167/iovs.15-17901

Figure 5.

Figure 5

(A, B) The OCR traces from control and degenerating retinas of mutant mice, as indicated. The OCR is not normalized against cytochrome a content. Arrows indicate the injection of uncoupler or rotenone (1 μM final concentration) in the sample well. Number of retinal samples is shown. Error bars: SEM. (C, D) OCR recordings of retina from retinal disease mutants normalized to pmol cytochrome a/sample. Number of retinal samples is shown. Error bars: SEM. (E, F) Larger residual respiratory capacity in retinal disease mutants undergoing degeneration was evidenced by a lower basal/maximal (%) OCR. Error bars: SEM; *P < 0.0001 compared to wild type, with 1-way ANOVA and Dunnett's post hoc test.