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. 2015 Dec 31;56(13):8438–8448. doi: 10.1167/iovs.15-17523

Figure 5.

Figure 5

Patterns of proinflammatory cytokine induction in the PMU and EAU aqueous. Cytokine levels from the aqueous in PMU (solid line) and EAU (dotted line) were measured on days 2, 7, 14, and 21 (EAU only). Each point represents the average from eight animals (16 eyes) analyzed per day. Bars indicate SE. (A) CXCL10, IL-1β, IL-18, and leptin demonstrate a pattern of a monophasic induction corresponding with the peak of clinical inflammation in both models (day 2 in PMU and day 14 in EAU). (B) RANTES, LIX, VEGF, MCP-1, MIP-1α, IL-17A, and GRO/KC are not induced in PMU but are induced in EAU. (C) Interleukin-6 demonstrates a concordant peak in PMU but not EAU.