The flow-pressure relationship of mouse eyes perfused while exposed to room air or while immersed to the limbus in a bath of isotonic saline. In both cases, eyes were covered with moist tissue paper and perfused at room temperature (RT) via the AC. The zero-pressure intercept (representing the pressure-independent outflow rate, Fu) was nonzero in eyes exposed to room air, but was indistinguishable from zero in immersed eyes. The slope of the flow-pressure relationship (representing the pressure-dependent outflow facility, C) was similar in both cases. Error bars, SD.