Table 1.

Scope of Enantioselective C–H Silylation^a

^aIsolated yields for reactions conducted on a 1.0 mmol scale following purification by silica gel chromatography. The ee values were determined by chiral HPLC analysis. The absolute configuration was assigned by analogy (see SI for details).

^b5.0 mmol scale.

^cThe ee values were determined after iodination.

^dThe reaction was conducted at 80 °C.

^e0.1 mol % [Ir(cod)OMe]₂ was used for the first step.

^fThe corresponding diarylmethanol was used as a substrate.

^gThe ee value was determined after Tamao–Fleming oxidation.

^hThe reaction was conducted at room temperature.