Table 2. Observed values.
Visit 1 (3–6 months) | Visit 2 (6–12 months) | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
ART-Def | ART-Early | ART-Def | ART-Early | |||||||||
Variable | mean | SD | n | mean | SD | n | mean | SD | n | mean | SD | n |
Visit age | 102.6 | 33.9 | 24 | 118.4 | 36.2 | 42 | 263.0 | 57.2 | 12 | 265.2 | 71.5 | 22 |
Birth weight | 2962.9 | 551.7 | 24 | 2930.2 | 396.3 | 42 | 2727.1 | 390.4 | 12 | 2895.5 | 405.9 | 22 |
CD4+ (%) | 32.9 | 7.9 | 24 | 37.7 | 8.4 | 42 | 34.5 | 7.6 | 12 | 37.9 | 6.0 | 22 |
CD38+ (% of CD8+) | 99.1 | 0.8 | 18 | 97.6 | 2.0 | 30 | 97.8 | 3.8 | 8 | 97.7 | 2.5 | 12 |
HLA-DR+ (% of CD8+) | 38.0 | 17.6 | 18 | 10.9 | 8.8 | 31 | 22.9 | 19.7 | 7 | 21.9 | 16.7 | 12 |
CD95+ (% of CD8+) | 93.4 | 7.7 | 18 | 67.7 | 27.5 | 31 | 87.0 | 11.5 | 7 | 73.4 | 22.3 | 12 |
CD161+/56+/16+ (% of NK) | 55.4 | 16.5 | 18 | 52.4 | 16.5 | 31 | 62.4 | 7.7 | 8 | 60.7 | 16.9 | 12 |
CD161+/56-/16- (% of NK) | 3.1 | 3.4 | 18 | 5.4 | 5.4 | 31 | 2.8 | 1.9 | 8 | 4.4 | 5.8 | 12 |
pDC | 0.3 | 0.1 | 17 | 0.3 | 0.2 | 29 | 0.4 | 0.7 | 8 | 0.4 | 0.4 | 11 |
CD28+ naïve (% of CD4+) | 76.1 | 9.5 | 18 | 75.7 | 8.7 | 31 | 69.7 | 7.4 | 8 | 70.3 | 11.3 | 12 |
CD27+ naïve (% of CD4+) | 80.5 | 8.5 | 18 | 83.6 | 9.3 | 31 | 78.4 | 10.4 | 8 | 80.7 | 5.7 | 12 |
CD28+ naïve (% of CD8+) | 40.8 | 20.5 | 18 | 56.7 | 18.7 | 31 | 36.7 | 18.7 | 8 | 49.6 | 18.4 | 12 |
CD27+ naïve (% of CD8+) | 53.7 | 18.1 | 18 | 74.5 | 16.8 | 31 | 54.5 | 16.2 | 8 | 67.8 | 14.2 | 12 |
Central Memory (% CD4+) | 19.7 | 8.3 | 18 | 21.1 | 8.7 | 31 | 17.7 | 11.2 | 8 | 22.6 | 8.4 | 12 |
Central Memory (% CD8+) | 22.9 | 12.5 | 18 | 11.8 | 5.7 | 31 | 20.9 | 4.0 | 8 | 16.9 | 6.1 | 12 |
CD38 MFI (on CD8+) | 1402.0 | 790.9 | 18 | 551.8 | 230.5 | 30 | 658.6 | 390.8 | 8 | 830.6 | 355.9 | 12 |
IL7 (pg/ml) | 4.1 | 3.7 | 16 | 5.4 | 4.4 | 28 | 4.0 | 3.6 | 11 | 4.9 | 3.4 | 21 |
Log10VL | 5.9 | 0.8 | 14 | 3.1 | 0.6 | 22 | 5.0 | 1.6 | 4 | 3.0 | 1.0 | 16 |
VL > 400 | - | - | 14 | - | - | 15 | - | - | 3 | - | - | 4 |