The expression of cytokine and chemokine was affected by BRMS1. Cytokines and chemokines analysis of (A) IL-8, (B) IL-15, (C) RANTES, (D) MCP-1, (E) GROα, (F) GMCSF, (G) IL-2 and (H) TNFα released from 231, 231/BRMS1, 435, 435/BRMS1 and A549 cells. Cells were exposed to DOX for 0 h (control), 4 h, 12 h and 24 h before measurement. Unit of Y-axis: pg mL−1. Error bars are standard deviation of the mean (*p < 0.05; B represents as BRMS1 in the figure).