Table 4. Comparison of immune markers between high and low metabolism groups.
| Low metabolism SUVmax<4.5, N = 40 | High metabolism SUVmax≥4.5, N = 78 | Total, N = 118 | P | |
|---|---|---|---|---|
| NLR | ||||
| Median (range) | 2.2 (1.2–19.5) | 2.8 (0.8–19.0) | 2.5 (0.8–19.5) | 0.604c |
| Mean ± SD | 3.3 ± 3.5 | 3.7 ± 3.2 | 3.5 ± 3.3 | 0.874d |
| Range | ||||
| <2.5 | 25 (62.5%) | 34 (43.6%) | 59 (50.0%) | 0.105b |
| 2.5–4.4 | 9 (22.5%) | 31 (39.7%) | 40 (33.9%) | |
| ≥4.5 | 6 (15.0%) | 13 (16.7%) | 19 (16.1%) | |
| Difference of NLR a (ΔNLR) | ||||
| < 0 | 22 (56.4%) | 50 (68.5%) | 72 (64.3%) | 0.220b |
| ≥ 0 | 17 (43.6%) | 23 (31.5%) | 40 (35.7%) | |
| Lymphocyte | ||||
| < 2000 | 32 (80.0%) | 57 (73.1%) | 89 (75.4%) | 0.501b |
| ≥ 2000 | 8 (20.0%) | 21 (26.9%) | 29 (24.6%) |
NLR, neutrophil to lymphocyte ratio; SUVmax, maximum standard uptake value.
a (NLR after one cycle of chemotherapy)—(initial NLR)
b P values were calculated using the Fisher’s exact test
c P values were calculated using the Logistic regression
d P values were calculated using the Independent t-test