Table 2. Incidence and multiplicity of hepatic neoplasms and FCA in the experimental mice (32 weeks-groups).
| Treatment | Incidence | Multiplicity (no. of neoplasms/mouse) | |||||
|---|---|---|---|---|---|---|---|
| Mice type | No. mice examined | Adenoma | HCC | Total | Adenoma | HCC | |
| saline | Wild | 6 | 0/6 (0%) | 0/6 (0%) | 0 | 0 | 0 |
| saline | IDO(-/-) | 7 | 0/7 (0%) | 0/7 (0%) | 0 | 0 | 0 |
| DEN | Wild | 13 | 6/13 (46%) | 4/13 (31%) b | 1.85±2.94 a,c | 1.00±1.68 | 0.85±1.46 c |
| DEN | IDO(-/-) | 14 | 2/14 (14%) | 0/14 (0%) | 0.14±0.36 | 0.14±0.36 | 0 |
a Mean±SD.
b p<0.05 (Significantly different from DEN (-/-) group by Fisher's exact probability test)
c p<0.05 (Significantly different from DEN (-/-) group by Tukey-Kramer multiple comparison test)