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Hierarchical flow-chart from the Chicago classification version 3.0. IRP, integrated relaxation pressure; ULN, upper limit of normal; DL, distal latency; DCI, distal contractile integral; PEP, panesophageal pressurization; EGJ, esophagogastric junction; DES, distal esophageal spasm. Adapted from Kahrilas et al16 with permission of Wiley.
