Table 2. List of clusters with significant CBF increases after levodopa administration.
MNI coordinates of the peak voxel are given in mm, as well as the number of voxels in each cluster and FWE p-value. Mean percent CBF changes were calculated from a 5 mm radius sphere centered at the peak voxel.
| x, y, z, mm | No. voxels | FWE p-value | label | % CBF change |
|---|---|---|---|---|
| 0, −70, 33 | 2,695 | 0.016 | Cuneus, precuneus | 33.4 |
| 56, −24, 34 | 3,046 | 0.020 | SupraMarginal (LA), Frontal_Inf_Oper (LA), Postcentral (LA), Precentral (LA) | 26.9 |
| 4, −33 −9 | 544 | 0.027 | Midbrain | 73.6 |
| 20, −6, −3 | 1,150 | 0.029 | Pallidum (LA), putamen (LA) | 44.0 |
| −60, 11, 9 | 461 | 0.030 | Frontal_Inf_Oper (MA) | 50.6 |
| 10, −64, −5 | 863 | 0.030 | Lingual (LA) | 33.0 |
| −48, 8, 39 | 428 | 0.031 | Precentral (MA) | 31.0 |
| −34, −46, 60 | 314 | 0.043 | Parietal_Inf (MA) | 61.1 |
| 34, −79, 9 | 108 | 0.043 | Occipital_Mid (LA) | 40.9 |
| −40, −18, 30 | 146 | 0.044 | Postcentral (MA) | 47.1 |
| 38, −69, 15 | 77 | 0.044 | White matter | 47.8 |
| −40, −57, −23 | 108 | 0.045 | Cerebelum_6 (LA) | 36.2 |
| 40, −27, −6 | 57 | 0.045 | White matter | 32.1 |
| −27, −85, 7 | 59 | 0.045 | Occipital_Mid (MA) | 47.3 |
| −58, −45, 39 | 77 | 0.047 | Parietal_Inf (MA) | 30.1 |
| −8, −28, −14 | 2 | 0.048 | Midbrain | 62.5 |
| 38, −39, 6 | 26 | 0.049 | White matter | 85.8 |
| −50, 30, 25 | 5 | 0.050 | Frontal_Inf_Tri (MA) | 41.8 |
Notes.
- MA
- more affected
- LA
- less affected
Note that left cerebellum was designated as less affected because motor fibers decussate in the medulla oblongata.