Fig 2. sEH gene disruption aggravated I/R-induced impairment of renal function.

Kidney function was evaluated by measuring the serum levels of creatinine (A) and urea (B) two days after reperfusion. sEH-KO mice presented significantly stronger increases of serum creatinine and urea levels compared to the WT-I/R or uninephrectomized control groups. Data are given as mean ± SEM (n = 5–8 per group). ***p<0.001 vs WT.