. 2016 Jan 4;11(1):e0145939. doi: 10.1371/journal.pone.0145939

Table 2. Various serum and hepatic parameters of rats in each group.

Feeding group	Control	HFC	HFC/control		Control	HFC	HFC/control	Control	HFC
	2 weeks	2 weeks	2/6 weeks	2/12 weeks	8 weeks	8 weeks	8/6 weeks	14 weeks	14 weeks
Serum TG (mg/dL)	36.2 ± 13.1	41.2 ± 5.4	37.2 ± 6.7	37.7 ± 13.5	37.3 ± 9.3	28.5 ± 11.1^a	39.2 ± 18.1	41.8 ± 7.7	79.2 ± 62.7
Serum TC (mg/dL)	50.8 ± 1.6	199.9 ± 159.6^a	59.7 ± 4.4^b	65.7 ± 6.3^b	61.3 ± 5.2	265.7 ± 157.1^a	83.6 ± 10.9^b	68.7 ± 2.8	1,593 ± 884^a
AST (IU/L)	122 ± 12	246 ± 162^a	89 ± 8^b	115 ± 16^b	105 ± 10	545 ± 208^a	110 ± 9^b	118 ± 21	1,121 ± 319^a
ALT (IU/L)	47 ± 3	94 ± 14^a	54 ± 4^b	56 ± 15^b	52 ± 4	220 ± 65^a	94 ± 19^a^,^b	50 ± 6	387 ± 87^a
Hepatic TG (mg/g liver)	19.2 ± 3.0	56.3 ± 26.6^a	41.3 ± 2.3^a	23.7 ± 2.8^a^,^b^,^c	18.0 ± 5.2	35.6 ± 11.6^a	21.6 ± 3.2^b	16.0 ± 2.8	28.3 ± 8.1^a
Hepatic TC (mg/g liver)	2.0 ± 0.4	115.1 ± 22.6^a	24.9 ± 7.5^a^,^b	2.6 ± 0.4^a^,^b^,^c	2.0 ± 0.1	128.8 ± 11.0^a	62.4 ± 11.0^a^,^b	1.9 ± 0.2	166.3 ± 33.3^a

Values are expressed as means ± SD (n = 6 rats); P < 0.05 was considered statistically significant.

^a Significantly different from control group rats of the same age.

^b Significant differences were observed between control diet intervention for 6 or 12 weeks and HFC diet feeding for 2 or 8 weeks.

^c Significant differences were observed between groups of control diet intervention for 6 and 12 weeks.

TG, triacylglycerol; TC, total-cholesterol; AST, aspartate aminotransferase; ALT, alanine aminotransferase.