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. Author manuscript; available in PMC: 2016 Jun 26.
Published in final edited form as: J Alzheimers Dis. 2015;46(4):901–912. doi: 10.3233/JAD-142943

Table 3.

Area under the curve (AUC), odds ratios, and positive and negative predictive values predicting Aβ status from biomarkers.

AUC Odds
Ratio
PPV NPV
Mini-Mental Status Examination 0.61±0.03 1.94±0.60 0.71±0.05 0.43±0.05
AVLT Trial 5 Recall 0.65±0.03 3.01±0.36 0.75±0.04 0.50±0.05
AVLT 5-min Recall 0.65±0.02 2.50±0.44 0.73±0.05 0.47±0.04
AVLT 30-min Recall 0.67±0.02 2.46±0.52 0.73±0.05 0.48±0.06
AVLT Recognition Discrimination 0.64±0.03 2.44±0.55 0.73±0.02 0.48±0.07
Retention 0.67±0.03 2.48±0.48 0.73±0.03 0.47±0.06
Trail Making Test A 0.62±0.02 2.13±0.46 0.73±0.04 0.44±0.05
Trail Making Test B 0.63±0.02 2.49±0.48 0.75±0.05 0.45±0.05
Boston Naming Test 0.59±0.02 1.66±0.17 0.70±0.03 0.42±0.04
Category fluency (animals) 0.60±0.02 1.88±0.43 0.71±0.05 0.42±0.03
Hippocampal volume 0.64±0.02 2.41±0.34 0.74±0.04 0.46±0.04
Medial Temporal Thickness 0.59±0.01 1.67±0.07 0.70±0.04 0.42±0.04
Precuneal Thickness 0.59±0.02 1.83±0.25 0.71±0.03 0.43±0.05
Mean Cortical Thickness of AD Meta-ROI 0.61±0.02 1.90±0.31 0.71±0.04 0.43±0.04
Mean FDG-PET SUVR of AD Meta-ROI 0.67±0.03 3.19±1.22 0.76±0.05 0.49±0.08
Principal component analysis of psychometric scores 0.68±0.02 3.38±1.16 0.71±0.03 0.56±0.10
Principcal component analysis of psychometric scores and imaging biomarkers 0.69±0.02 3.18±0.76 0.71±0.03 0.55±0.08
Principal component analysis of cortex-wide cortical thickness 0.59±0.03 1.57±0.21 0.67±0.04 0.43±0.02