Table 2.
Literature-based distances in complexes of eukaryotic ribosomes with tRNAs and mRNAs
| PDB ID (Method of Analysis and Resolution in nm) | Complex | Distance (nm) | Base in 3rd Position of the A Site Codon | Reference |
|---|---|---|---|---|
| 4KZZ (x-ray, 0.70) | 40S • tRNA (P site) • mRNA • eIF1Aa | 2.78 | U | (37) |
| 1VXZ (cryo-EM, 0.63) | 80S • tRNA (P site) • tRNA (E site) • mRNA | 2.74 | A | (36) |
| 4CXB (cryo-EM, 0.69) | 80S • tRNA (P site) • tRNA (A site) • mRNA | 2.58 | U | (35) |
Distances between the P of the 5′-terminal phosphate of mRNA codon at the P site and the C8 of A or C5 of U in the third position of the A site codon calculated from the structures of complexes of eukaryotic ribosomes with tRNAs and mRNAs deposited in the PDB.
a
eIF1A, eukaryotic translation initiation factor 1A.